Nous voudrions effectuer une description ici mais le site que vous consultez ne nous en laisse pas la possibilité. Best Answer: Yes. He can take benadryl while taking an antibiotic. If he is truly having an acute allergic reaction to his antibiotics, benadryl may be like throwing a glass of water onto a forest fire. Yes it is safe to take Benadryl it is not wise. You should take Sudafed or Mucenex these help drain the sinuses. Benadryl will dry up the secretions and they won't be easily expelled therefore the bacteria will stay in the sinus and your recovery will take longer. The two drugs basically do the same thing, and, as opposed to mixing say naproxen, Acetaminophen, and ibuprofen, there would be no … benefit - just more drowsiness and dry-mouth. Can you mix. Doctors give trusted answers on uses, effects, side-effects, and cautions: Dr. Grin on can you take amoxicillin and benadryl and ibuprofen together: Yes u can. Doctors give trusted answers on uses, effects, side-effects, and cautions: Dr. Grin on can you take amoxicillin and benadryl and ibuprofen together: Yes u can. Does Benadryl Interact with other Medications? Serious Interactions. These medications may interact and cause very harmful effects. Consult your healthcare professional (e.g., doctor or pharmacist. Mixing benadryl with antibiotics View drug interactions between amoxicillin and Benadryl. These medicines may also interact with certain foods or diseases.It is perfectly ok promethazine hydrochloride dosage for insomnia to take the two together (antibiotic and benadryl). What other drugs will affect Benadryl? Ask a doctor or pharmacist before using this medicine if you are also using any other drugs, including prescription and over-the-counter medicines, vitamins, and herbal products. As long as nothing bad's happened to you by using either, then it generally is safe. Benadryl is an antihistamine, and there's nothing major documented that shows antibiotics and antihistamines have any big effects on each other. Benadryl is an antihistamine and tends to have a drying effect on mucus membranes, also. Ibuprofen is an NSAID with anti inflammatory action. Nsaids, such as ibuprofen and aspirin, can also cause a thinning effect on the blood, temporarily.